Sakskøbing is a market town and station town on northeastern Lolland with 4,588 inhabitants (2020), located in Guldborgsund Municipality in the Region Zealand. The town is located on both sides of a narrow fjord passage in Sakskøbing Fjord, which to the northwest empties into Smålandsfarvandet and to the southeast runs together with Sakskøbing Å. On the crossing at Sakskøbing Harbor, a bridge connects the two districts via Brogade, and east-west the city is intersected by a long main street.

Although Sakskøbing is an old market town, it appears in many respects as a modern city. On the north side of the fjord, a new residential area with apartments has been built, while on the south side, a harbor silo, Qvades Silo, has been converted into a modern residential high-rise and industrial buildings have been turned into lucrative commercial properties. A large part of Sakskøbing's other buildings have been renovated after the year 2000, which gives the impression of a well-maintained exterior for observers. The modern is emphasized by the city's landmark, the smiling water tower Saxine, which in 1982 had a smiling girl's face painted at the suggestion of the architect Flemming Skude.

In Sakskøbing there are also a number of older and old buildings. Sakskøbing Church was originally built as a village church in 1250 (dedicated to the apostles Peter and Paul), but subsequently expanded with a tower and nave in the following centuries. The tower, completed with spiers in 1852, is 48 meters high. Hotel Saxkjøbing dates back to around the year 1800, and is today also a restaurant run by Claus Meyer

Sakskøbing is located close to the E47 motorway and intersects in its southern part of secondary route 153. From the center there are 9 kilometers to Maribo, almost 19 to Nykøbing Falster, 26 to Rødbyhavn, almost 32 to Vordingborg and 35 kilometers to Nakskov. Until 1 January 2007, the city was the headquarters of Sakskøbing Municipality in Storstrøm County.