Palazzo Barbaro is located in the San Marco district at number 2947 in Campo Santo Stefano. Built in the 16th century, it is located on the corner of Palazzo Loredan, headquarters of the Veneto Institute of Sciences, Letters and Arts.
The building dates back to the 16th century by the noble Barbaro family. In 1700 Daniele Barbaro became owners and after 1797 Marco Barbaro. Since 1704 the building had been pledged to Andrea Baffo, father of the poet Giorgio Baffo.
The facade was originally frescoed by Sante Zago, a contemporary of Tintoretto, even if this work of art has been lost over time. The front of the building faces Rio del Duca with round windows. The facade on Campo Santo Stefano is instead composed of two portals, six Renaissance windows per floor and horizontal stringcourses.